Exploring natural products-based cancer therapeutics derived from egyptian flora

Egyptian plants are a rich source of natural molecules, representing considerable biodiversity due to climate variations between the Northern, Southern, Eastern and Western regions country. Sinai is considered precious nature reserves preserving flora, fauna, marine organisms, historical habitats with ancient origins. Here, traditional medicinal approaches have been used for hundreds years. Healthy lifestyles, low levels stress microbial infections, dependence on flora herbal medicine might in combination explain why burden cancer lower some than others. The primary aim this review document products that as foods medicines Egypt, general, Sinai, particular, focus those demonstrated anticancer activities. documented uses these described, together their chemical pharmacological activities reported outcomes clinical trials against cancer. A literature search was performed identify texts describing cultivated grown including information found textbooks, published articles, plant list website (http://www.theplantlist.org/), names services (http://mpns.kew.org/mpns-portal/), web databases (PubMed, Science Direct, Google Scholar). We collected data most or Egypt previously investigated effects identified bioactive elements. Several species, belonging different families associated 67 compounds, were potential agents (in vitro studies). potent cytotoxic Asteraceae, Lamiaceae, Chenopodiaceae, Apocynaceae, Asclepiadaceae, Euphorbiaceae, Gramineae, Liliaceae. such Punica granatum L., Nerium oleander Olea europea Matricaria chamomilla Cassia acutifolia Nigella sativa Capsicum frutescens Withania somnifera Zingiber officinale Roscoe, examined trials. Among various habitats, we North New-Delta, Giza Governorates. In review, highlight role played by current therapies possibility may be further studies development drugs. These extracts form basis isolation phytochemicals Some active components derived from applied preclinical settings, resveratrol, quercetin, isoquercetin, rutin.